Dosage Guidelines provides typical dosing ranges for adults and pediatrics, plus renal/hepatic adjustments and max daily doses. Always individualize and consult labeling.

Amlodipine

Adults: 5–10 mg PO once daily. Start 2.5 mg in frail/elderly or hepatic impairment. Max 10 mg/day.

Metformin

Immediate-release: start 500 mg PO BID with meals; titrate weekly; max 2550 mg/day. Avoid if eGFR < 30 mL/min/1.73m².